Annual Request for Application (RFA) – Innovation Projects

The mission of the Duke Institute for Health Innovation (DIHI) is to catalyze transformative innovations in health and healthcare, and to help cultivate a community of innovation and entrepreneurship across Duke University and the health enterprise. Our annual request for innovation applications is open to all faculty, staff, students, and trainees across Duke University and Duke University Health System.

At DIHI, we look for innovative but practical ways in which we can have measurable impact on the health and wellness of our patients and our people. At the same time, we are committed to fostering an ecosystem that is conducive to the creation, development, integration and scaling of novel ideas through transformative partnerships and strong collaboration. In the end, innovation is very much a team science.

-- Suresh Balu, MS, MBA, Executive Director for DIHI, and Associate Dean, Innovation and Partnership for School of Medicine

DIHI RFA 2026 RFA

We are excited to announce the 2026 Duke Institute for Health Innovation (DIHI) RFA for selecting and implementing innovative solutions in our clinical enterprise. The proposals should provide impactful solutions to significant issues encountered by care providers, patients and their loved ones and represent urgent health challenges nationally.

For the 2026 funding cycle, priority will be given to ideas aligned with the thematic area of harnessing the power of AI to proactively solve critical healthcare challenges, improving operational efficiency and transforming patient care.

This year, we’re hosting Gen AI Innovation Clinics where you can bring your ideas and problems and explore the possibilities of generative AI. You’ll get to collaborate and design solutions and create impactful proposals that align with our focus on AI-enabled healthcare innovation

Proposals are due by 11:59 PM, November 7, 2025.

All proposals are required to have a DUHS operational lead as a co-sponsor to be accepted for review. We look forward to your innovative solutions.

Up to ten applications will be selected for support. Most proposals are expected to request funding in the range of $25,000 to $60,000 over a one-year period. For reference, this funding does not cover faculty time.

Question? Please email DIHIrfa@duke.edu

Download Information Packet

DIHI 2026 RFA Timeline
Oct 6, 2025 DIHI RFA open for submission
Nov 7, 2025 11:59 PM Application due date
Feb 2026 Finalists – Presentation to leadership
Apr 2027 Funding start
Nov 2026 Midpoint reporting

If you have any questions or would like to discuss your innovation with us, please join our RFA office hours Wednesdays at 2:30 – 3:00 PM and Thursdays at 1:30 – 2:30 PM.

DIHI RFA 2025 RFA

The Duke Institute for Health Innovation (DIHI) closed the emerging ideas and innovation funding cycle. Applications were open to address actual, important problems encountered by care providers, patients and their loved ones in our clinical enterprise, and to represent urgent national health challenges.

For the 2025 funding cycle, priority was given to ideas aligned with the thematic area of improving provider and staff experience, patient journey, and clinical outcomes using advanced technology solutions.

Our commitment to innovation at Duke Health remains strong, as evidenced by the strong slate of projects brought forward by our clinical teams at the forefront of patient care. The winning teams, selected from a highly competitive pool of applications will have significant impact on automating processes, helping us realize greater efficiencies while bringing the highest-quality care to our patients.

-- Tom Owens, MD, Executive Vice President and Chief Operating Officer of Duke University Health System (DUHS) and Executive Director for DIHI

DIHI RFA 2024 RFA

For the 2024 funding cycle, priority was given to ideas in Generative AI & Large Language Models: AI solutions to improve staff and clinician efficiency, patient journey and outcomes.

Our commitment to innovation at Duke Health remains strong, as evidenced by the strong slate of projects brought forward by our clinical teams at the forefront of patient care. The winning teams, selected from a highly competitive pool of applications will have significant impact on automating processes, helping us realize greater efficiencies while bringing the highest-quality care to our patients.

-- Tom Owens, MD, Executive Vice President and Chief Operating Officer of Duke University Health System (DUHS) and Executive Director for DIHI

DIHI RFA 2023 Projects

DIHI RFA 2022 Projects