Catalyzing Transformative Innovations in Health & Healthcare

The mission of the Duke Institute for Health Innovation (DIHI) is to catalyze transformative innovations in health and healthcare, and to help cultivate a community of innovation and entrepreneurship across Duke University and the health enterprise.

Annual Request for Applications

In alignment with the its mission, the Duke Institute for Health Innovation is constantly seeking out innovations in care delivery. The annual request for applications (RFA) is a mechanism for designing and implementing innovations to address actual and important problems encountered by care providers, patients and their loved ones, and represent urgent health challenges nationally. The RFA is open to all faculty, staff, students, and trainees across Duke University and Duke University Health System.

The 2027 Duke Institute for Health Innovation (DIHI) Request for Applications is now open. We invite you to bring forward bold, practical, and scalable ideas that address high-priority challenges across our clinical enterprise. 

This year’s cycle is focused on solutions that can accelerate transformation in the following areas:

  • AI-powered solutions for a virtual care platform;
  • Automation and workflow redesign; and
  • Sustainable, patient-facing AI solutions.
DIHI 2027 RFA Timeline
Sept 3, 2026 DIHI RFA open for submission
Oct 17, 2026 11:59 PM Application due date
Feb 2027 Finalists – Presentation to leadership
May 2027 Funding start
Nov 2027 Midpoint reporting

Our Focus

Innovation Science & Implementation

Positively impacting clinical care in the real world by putting innovations into practice.

Technology & Innovation Infrastructure

Increasing the speed to deliver value and expanding the potential for achievable innovation.

Workforce Training & Education

Expanding the capabilities of the individuals that make innovation possible.

Featured Projects

From the Blog

How We Innovate: By the Book

At our institute, we don’t just talk about innovation—we live it. Theories and strategies from some of the greatest thinkers on disruption and discovery guide our work daily. Below, we highlight key quotes from The Innovator’s Dilemma and The Idea Factory, showing how we intentionally follow their advice. Compiled and

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‘Model Facts’ v2 label for HTI-1 compliance

Our team at the Duke Institute for Health Innovation published the first AI product label in healthcare in March 2020 in Nature Digital Medicine. The manuscript describing the ‘Model Facts’ label and the initial example are available here. The first Model Facts label was for the Sepsis Watch model. The publication

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